Immunohistochemistry and Pathology

Comparative Analysis of Specific Expression of Melanoma-Associated Antibodies


Melanoma-associated antigens (MAA’s) can be recognized by autologous T lymphocytes, including Melan-A/MART-1, MAGE-1, MAGE-3, Tyrosinase, gp100, gp75, BAGE-1, GAGE-1. The Melan-A/MART-1 antigen is expressed in over 90% of human melanomas and melanocytes. Except for retinal tissue, Melan-A/MART-1 RNA is not expressed in the vast majority of normal tissues, nor is it expressed in tumors occurring in the colon, breast, brain, kidney, lung, bone, etc.


Expression of various melanoma markers and other markers in 12 cases of melanoma and 1 case of cutaneous metastatic hepatocellular carcinoma

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